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Is treatment with platelet-rich fibrin better than zinc oxide eugenol in cases of established dry socket for controlling pain, reducing inflammation, and improving wound healing?

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Paul Sam, Choudhury Rupshikha, Kumari Nandini, Rastogi Sanjay, Sharma Ashish, Singh Vikas, Laskar Shyamalendu, Dubey Tushar,
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 ( Paul Sam ) - Educare Institute of Dental Sciences Department of Orthodontics and Dentofacial Orthopaedics
 ( Choudhury Rupshikha ) - Regional Dental College Department of Oral and Maxillofacial Surgery
 ( Kumari Nandini ) - Banaras Hindu University Faculty of Dental Sciences Trauma Centre
 ( Rastogi Sanjay ) - Kothiwal Dental College and Research Center Department of Oral and Maxillofacial Surgery
 ( Sharma Ashish ) - Kothiwal Dental College and Research Center Department of Oral and Maxillofacial Surgery
 ( Singh Vikas ) - Teerthanker Mahaveer Dental College and Research Centre Department of Public Health Dentistry
 ( Laskar Shyamalendu ) - Kothiwal Dental College and Research Center Department of Oral and Maxillofacial Surgery
 ( Dubey Tushar ) - Kothiwal Dental College and Research Center Department of Oral and Maxillofacial Surgery

Abstract


Objectives: To appraise the effectiveness of platelet-rich fibrin (PRF) in the management of established dry socket in terms of pain, inflammation, and wound healing.

Materials and Methods: Two hundred patients with established alveolar osteitis were studied to determine the efficacy of PRF and zinc oxide eugenol (ZOE) for pain control, inflammation reduction, and wound healing. Patients were randomly allocated to Group A (PRF) or Group B (ZOE). Patients were examined on the 1st, 3rd, 7th, and 14th postoperative day and evaluated for pain using visual analogue scale scores, inflammation with a gingival index score, and wound healing through a determination of the number of bony walls exposed.

Results: Group A showed better results in terms of pain remission, control of inflammation, and wound healing compared to Group B. Results between groups were statistically significant (P<0.05).

Conclusion: PRF is a better alternative than ZOE for the effective management of alveolar osteitis.

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Dry socket; Pain; Platelet-rich fibrin; Wound healing

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